Time Line- Development of Glycoscience and Glyconutritionals
1880s - Characterization of monosaccharides by Emil Fischer.
1952 - Fresh, not aged, Aloe gel heals radiation burns on rabbits (Clarence C. Lushbaugh, Cancer 1953 vol. 6).
1970 - 500 glycobiology papers published.
1976 - Research paper identifies the 8 sugars found in biological glycoproteins and glycolipids.
1980 - 1500 glycobiology papers published.
1988- Dr. John Axford publishes his "Glucose only theory"
in British Journal (glucose is not the only needed sugar)
1990 - 4000 glycobiology papers published.
1990 - Journal of Glycobiology started by Oxford University.
1990 - "Capitalizing on Carbohydrates" by John Hodgson in BioTechnology Vol 8 Feb. 1990 109 discussing cell surfaces containing carbohydrates involved in intercellular communication and essential for immune function.
1992 - Active component in Aloe gel is stabilized.
1994 - A Research and Development Company is established as a glyconutritional company.
1995 - Nature: cell surface sugars necessary for recognition and immune function.
1996 - Harper's Biochemistry, Murray et al.: chapter on glycoproteins focuses on the 8 necessary sugars used in glycoproteins and glycolipids for cellular communication.
1996 - Patent application is filed for composition and use of a glyconutritional supplement.
1996 - Glyconutritional Company begins marketing glyconutritional supplement.
1998 - Acta Anatomica: special March issue on glycoscience; emphasizes that information content of biological sugar combinations exceeds that of the DNA code.
1998 - South Africa issues world's first patent for a glyconutritional blend
1998 - Healthy humans given radiologically labeled galactose, mannose and glucose incorporate all three directly into glycoproteins, proving that the body uses the different sugars as nutrients directly from the diet, instead of manufacturing them all from glucose alone.
2000 - 8000 glycobiology papers published.
2000 - Launch in March of Health and Nutrition Glycoscience website.
2000 - Newton Graphic Science Magazine: the science of cellular messaging.
2001 - Science: March 23 issue features "Carbohydrates and Glycobiology"; reviews structural and functional uses of 8 critical sugars in cellular physiology.
2001 - Physicians Desk Reference (PDR ) for Non-Prescription Drugs and Dietary Supplements: lists for the first time glyconutrient blend, phytosterol complex, and phytochemical complex.
2001 - Singapore, New Zealand, and Australia issue patents glyconutritional blend
2001 - NIH grants consortium $34 million to study cell-cell communication interactions.
2002 - Australian Journal of Chemistry 55(2): Carbohydrates Special Issue.
2002 - The Scientist 16:9 April 29 "Glycobiology Goes to the Ball."
2002 - Yahoo lists 15,000 entries for the glyconutrient "mannose."
2002 - France, Germany, Ireland, Italy, Liechtenstein, Spain, Switzerland, and the United Kingdom issue patents for a glyconutritional formula
2002 - Scientific American: July "Sweet Medicine: Building Better Drugs from Sugars."
2002 - New Scientist Archive: October story quotes JHU biochemist emphasizing glycobiology as the future of immunology, neurology, developmental biology, and disease research.
2002 - CAM: Volume 2, Issue 5 - December 2002 "Arthritis - Using the New Glyconutritionals."
2003 - Yahoo lists 63,000 entries for the glyconutrient "mannose."
2003 - Mexico and Hong Kong issue patents for a glyconutritional formula.
2003 - Advanced Glyconutrient-Antioxidant formulation is developed.
2004- Taiwan and Philippines issue patents for a glyconutritional formula.
2005- USA issues patent for glyconutritional formula
Sunday, November 07, 2004
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2 comments:
Thank you for this information. John Thomson
The disease process is an impairment of health or a condition of abnormal functioning. This is the case regardless of which disease you are confronted with. Each disease attacks the human body in various ways, by targeting a specific type of cell, organ or system in your body.
The human body is extremely complex, there are 46 human chromosomes (22 pairs of autosomal chromosomes and 2 sex chromosomes) between them house almost 3 billion base pairs of DNA that contains about 30,000 - 40,000 protein-coding genes.
At a microscopic level, we are all composed of cells. Look at yourself in a mirror -- what you see is about 10 trillion cells divided into about 200 different types. Our muscles are made of muscle cells, our livers of liver cells, and there are even very specialized types of cells that make the enamel for our teeth or the clear lenses in our eyes!
We are not defining disease, we are not curing disease in fact what we are focusing on is the basis of how the human body functions at the level of the cell. There is nothing more important then the function of cellular communication.
Each of your body systems are interconnected and dependent on each other. Your heart, which is part of your circulatory system, does not beat unless your brain, which is part of your nervous system, tells it to. Your skeletal system is dependent on your digestive system for increase in size and strength. Your muscular system needs your respiratory and circulatory systems to supply energy in the form of oxygen and nutrients. All of these systems must be functioning properly and working harmoniously together without impairment.
All of the information communicated amongst and in-between these bodily systems are through the biological communication system through glycoforms and glycoproteins.
Any disease process interferes with many components of your bodies systems. Therefore your bodies systems are not functioning as they should be and the disease starts to cause problems.
Your body warns you that you have something wrong by expressing specific symptoms. Symptoms are those complaints or problems that you feel, and then you typically seek help from a doctor or other health care provider.
Let’s look at some of the dysfunctions caused by specific disease processes.
If your immune system is not functioning properly such is the case with people infected with HIV. Your situation in this case is that your body is not producing the appropriate amount of CD4 & CD8 cells vital for immune function.
People with diabetes do not properly produce insulin cells and these cells do not carry the insulin to the receptor sites, which is necessary to regulate sugars and starches.
People affected by cardiovascular diseases have a dysfunction of the heart and blood vessel systems (arteries, capillaries, veins) and when broken down are dysfunctions of specific cells. The most common dysfunction is when your cells have a buildup of fatty deposits that start to clog up. The cause not clearly identified though it is partly due to an imbalance of cholesterol and inflammation of the cells of the cardiovascular system.
People diagnosed with MS; the immune cells are mis-instructed to attack the myelin sheaths that cover our nerves.
Those with Lupus; the immune cells are mis-instructed to attack organs like the liver or the skin.
People with Type 1 diabetes immune cells are mis-instructed to attack islet cells in the pancreas that make insulin.
So ask yourself the following question
If every disease is a situation where there is a dysfunction of cellular activity then doesn’t it make sense to provide your body with what it requires to restore proper function to your body’s cells?
Health and wellness is where it’s at, it has always been this way (unfortunately in recent history science has been so focused on treating symptoms of disease as opposed to supporting health) and today more then ever science is focused on validating and supporting health.
You can restore cellular health by providing your body with the necessary essential nutrients it requires to support cellular communication functions.
By providing specific nutrients that your body requires to assemble the proper glycoforms on the surface of your cells, it can then begin to restore proper cellular function. Then your body utilizes the message coding glycoforms to monitor and balance your body's immune system and communication system functions. Now your body has the nutritional resources to enable your body to produce normal healthy cells in sufficient amounts.
So this is not a result of a cure, it is not a drug that is targeting a specific symptom it is simply providing specific nutrients that you need to support a function in your body. Your body is already pre-programmed to use the foods (nutrients) to support and maintain health.
Regardless of what disease or system impairment that you are faced with all of them are classified as dysfunctions of your body's systems, meaning these systems are not functioning the way they are supposed to.
All 6 billion people on earth require specific nutrients to support their body's natural physiological functions at the cellular level.
It is a matter of ensuring you are getting the right nutrients in the right amounts on an ongoing daily basis to support specific functions that occur naturally in your body so that all of your body's systems are functioning the way they are intended to work.
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